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Philippe Clézardin Selected Research

Conditioned Culture Media

1/2018miRNA-30 Family Members Inhibit Breast Cancer Invasion, Osteomimicry, and Bone Destruction by Directly Targeting Multiple Bone Metastasis-Associated Genes.
1/2017Lysyl Oxidase Is a Strong Determinant of Tumor Cell Colonization in Bone.
12/2006Transmigration: a new property of mature multinucleated osteoclasts.

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Philippe Clézardin Research Topics

Disease

57Neoplasms (Cancer)
01/2021 - 08/2002
54Neoplasm Metastasis (Metastasis)
11/2021 - 08/2002
42Breast Neoplasms (Breast Cancer)
01/2021 - 08/2002
21Bone Resorption
01/2021 - 11/2002
8Bone Diseases (Bone Disease)
10/2020 - 06/2005
7Osteolysis
10/2020 - 06/2005
6Prostatic Neoplasms (Prostate Cancer)
12/2018 - 01/2005
3Carcinogenesis
01/2021 - 09/2005
3Multiple Myeloma
01/2015 - 08/2012
2Disease Progression
09/2011 - 09/2005
2Melanoma (Melanoma, Malignant)
07/2010 - 11/2008
2Ovarian Neoplasms (Ovarian Cancer)
06/2006 - 12/2004
1Brain Neoplasms (Brain Tumor)
01/2021
1Colorectal Neoplasms (Colorectal Cancer)
01/2017
1Rheumatoid Arthritis
01/2014
1Obesity
01/2014
1Fibrosis (Cirrhosis)
01/2014

Drug/Important Bio-Agent (IBA)

27Diphosphonates (Bisphosphonates)IBA
12/2018 - 11/2002
9Biomarkers (Surrogate Marker)IBA
01/2021 - 12/2010
8Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2018 - 07/2003
8Zoledronic Acid (Zometa)FDA Link
12/2018 - 02/2007
7lysophosphatidic acidIBA
08/2015 - 12/2004
5MicroRNAs (MicroRNA)IBA
01/2021 - 08/2014
5Lysophosphatidic Acid ReceptorsIBA
03/2014 - 12/2004
4Messenger RNA (mRNA)IBA
01/2021 - 09/2011
4Proteins (Proteins, Gene)FDA Link
12/2018 - 09/2008
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2017 - 06/2007
4Pharmaceutical PreparationsIBA
01/2016 - 10/2009
4Risedronic Acid (Actonel)FDA LinkGeneric
11/2012 - 11/2008
4NitrogenIBA
07/2011 - 09/2008
3Bone Density Conservation AgentsIBA
11/2021 - 09/2008
3Cathepsin KIBA
11/2018 - 10/2007
3PeriostinIBA
11/2018 - 01/2011
3Conditioned Culture MediaIBA
01/2018 - 12/2006
3Estrogen ReceptorsIBA
01/2018 - 09/2011
3OsteoprotegerinIBA
08/2017 - 07/2011
3Interleukin-6 (Interleukin 6)IBA
01/2017 - 12/2004
2Monoclonal AntibodiesIBA
01/2021 - 11/2014
2ERRalpha Estrogen-Related ReceptorIBA
01/2020 - 11/2016
2Extracellular Matrix ProteinsIBA
11/2018 - 09/2005
2Interleukin-8 (Interleukin 8)IBA
01/2018 - 12/2004
2CalciumIBA
12/2017 - 12/2002
2LigandsIBA
08/2017 - 07/2011
2Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA
01/2017 - 03/2011
2MineralsIBA
11/2015 - 11/2008
2LipidsIBA
08/2015 - 01/2009
2DenosumabFDA Link
06/2015 - 01/2015
2IntegrinsIBA
11/2014 - 08/2002
23- (4- (4- ((1- (2- chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acidIBA
01/2014 - 04/2012
2Clodronic Acid (Clodronate)IBA
02/2013 - 02/2007
2AndrogensIBA
01/2013 - 01/2005
2Biological ProductsIBA
12/2012 - 01/2009
2indolepropanol phosphate (IPP)IBA
11/2012 - 07/2011
2LuciferasesIBA
01/2008 - 02/2007
2Green Fluorescent ProteinsIBA
06/2007 - 02/2007
2adhesion receptorIBA
06/2007 - 08/2002
2CytokinesIBA
06/2006 - 12/2004
1Long Noncoding RNAIBA
01/2021
1Circular RNAIBA
01/2021
1Fibronectins (Fibronectin)IBA
01/2021
1Integrin alpha5IBA
01/2021
1Therapeutic UsesIBA
01/2021
1volociximabIBA
01/2021
1Oncogene Proteins (Oncogene Protein)IBA
01/2020
14- Acetamido- 4'- isothiocyanatostilbene- 2,2'- disulfonic Acid (SITS)IBA
01/2020
1NexusIBA
01/2020
1ChemokinesIBA
01/2020
1Antineoplastic Agents (Antineoplastics)IBA
12/2018
1Interleukin-11 (Interleukin 11)IBA
01/2018
1Progesterone Receptors (Progesterone Receptor)IBA
01/2018
1EpiregulinIBA
08/2017
1Epidermal Growth Factor (EGF)IBA
08/2017
1Calcium-Sensing ReceptorsIBA
08/2017
1A-Form DNA (A-DNA)IBA
08/2017
1Drug CarriersIBA
10/2015
1ClathrinIBA
10/2015
1Zinc Finger E-box-Binding Homeobox 1IBA
08/2015
1Calcium Channels (Calcium Channel)IBA
09/2014
1Tyrosine Kinase InhibitorsIBA
09/2014
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
09/2014
1Neutralizing AntibodiesIBA
09/2014
1vatalanib (PTK787)IBA
09/2014
1Bevacizumab (Avastin)FDA Link
09/2014
1Doxycycline (Periostat)FDA LinkGeneric
08/2014
1Transcription Factors (Transcription Factor)IBA
08/2014
1Heparin-binding EGF-like Growth Factor (HB-EGF)IBA
01/2014
1Estrogens (Estrogen)FDA Link
02/2013
1Mevalonic Acid (Mevalonate)IBA
11/2012
1Cell Surface ReceptorsIBA
11/2012
1Doxorubicin (Adriamycin)FDA LinkGeneric
11/2012
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
11/2012
1farnesyl pyrophosphate (farnesyl diphosphate)IBA
11/2012
1Phospholipids (Phosphatides)FDA LinkGeneric
04/2012

Therapy/Procedure

24Therapeutics
01/2021 - 11/2002
3Drug Therapy (Chemotherapy)
02/2013 - 12/2010
2Radiotherapy
11/2021 - 10/2020
2Palliative Care (Palliative Therapy)
10/2020 - 01/2003
2Castration
11/2016 - 01/2013
2Intravenous Injections
03/2010 - 02/2007
1Neoadjuvant Therapy
12/2018